Tree Position

R-U106/S21 > Z2265 > Z381/S263 > S264/Z156 > BY20378

Unique Mutations

The mutations unique to this man are summarized in the table below. Those with a '+' or '*' confidence level are considered by FamilyTreeDNA or FullGenomesCorp to be high quality SNPs/INDELs. For completeness, all other mutations of lesser confidence are included as well. These additional mutations may be useful for distinguishing between very closely related men.

Occasionally, some of the mutations listed here will be thought to be shared with other men in which case they might appear in upstream blocks on the tree. When this happens, the 'Blocks' field will indicate what block they appear in. Such a situation might arise with BigY men if the BED data suggests another man may be positive for a SNP, even though it doesn't appear in his VCF data. It might also happen if Chromo2 testing or Sanger sequencing of other men not on the tree show the SNP to be shared.

POS-REF-ALT (hg19) POS-REF-ALT (hg38) Blocks Names Region McDonald BED combBED STRBigY2
137970
19573282-A-G 17461402-A-G P5_Prx YA*
22306132-T-A 20144246-T-A DYZ19 A*
5458874-C-T 5590833-C-T A*
6175117-C-A 6307076-C-A IR3_Dst A*
20991160-A-AT 18829274-A-AT P4_Dst 18×TA*
26162049-C-CT 24015902-C-CT P1_Y1 A*
25534903-A-C 23388756-A-C P1_gr1 A*
19637542-C-T 17525662-C-T P5_Prx A*
7191562-G-C 7323521-G-C BY160576 YY+
7321213-CAG-C 7453172-CAG-C +
7348438-T-G 7480397-T-G BY160556 YY+
7728239-AAGTTCTGG-A 7860198-AAGTTCTGG-A +
7751098-T-G 7883057-T-G BY33328 YY+
7831514-G-A 7963473-G-A BY160469 YY+
9155348-C-T 9317739-C-T BY160222 Y+
8513274-C-A 8645233-C-A BY160339 YY+
17608558-G-A 15496678-G-A BY159572 YY+
9441648-C-T 9604039-C-T BY160206 YY+
17360111-C-A 15248231-C-A BY159619 YY+
9858320-G-A 10020711-G-A BY160174 YY+
17311043-G-T 15199163-G-T BY159634 YY+
17298306-A-G 15186426-A-G BY159635 YY+
17134405-G-A 15022525-G-A BY159668 YY+
16242567-T-C 14130687-T-C BY211636 YY+
15092767-T-A 12980855-T-A BY159970 YY+
17417807-G-T 15305927-G-T BY159607 YY+
17637771-G-A 15525891-G-A BY159571 YY+
13412208-C-T 11256532-C-T BY210200 +
17767486-T-A 15655606-T-A BY159544 YY+
28645641-AC-A 26499494-AC-A +
15237234-G-A 13125320-G-A CTS3873 Y+
18582391-C-A 16470511-C-A BY159408 YY+
14203179-C-T 12082473-C-T BY160092 YY+
23388968-G-A 21227082-G-A BY158816 YY+
22896817-A-G 20734931-A-G BY158912 YY+
14407916-G-C 12287214-G-C YY+
22824771-C-G 20662885-C-G BY158925 YY+
22466850-G-C 20304964-G-C BY221793 DYZ19 +
22024891-C-CA 19863005-C-CA +
21984574-T-C 19822688-T-C BY159058 YY+
21435829-G-A 19273943-G-A BY159153 YY+
6381832-T-A 6513791-T-A +
22608255-CTTTAAG-C 20446369-CTTTAAG-C +
7683736-A-G 7815695-A-G BY160494 YY+
14534935-G-A 12423136-G-A BY160026 YY+
2909944-T-C 3041903-T-C BY160700 YY+
14872096-A-G 12760166-A-G BY159997 YY+
22561830-G-GT,GTT 20399944-G-GT,GTT 13×T*
14180719-TC-T 12060013-TC-T **
6654004-T-TA 6785963-T-TA 8×A**
22855074-G-A 20693188-G-A **
24353155-C-CT 22207008-C-CT P3_t1 10×T**
24408752-C-A 22262605-C-A **
14025598-GAAAGAAAGAAAGAGAGAGAAAGAAAGAAA-G 11904892-GAAAGAAAGAAAGAGAGAGAAAGAAAGAAA-G **
10772665-C-G **
11001681-G-T **
10962914-A-T **
13521917-A-AT 11366241-A-AT 10×T**
14443-G-T **
9832670-A-G 9995061-A-G FGC61989 **
11020272-C-A **
3600130-C-A 3732089-C-A **
4678438-T-C 4810397-T-C **
4832792-C-A 4964751-C-A **
5271439-C-A 5403398-C-A **
9832679-A-C 9995070-A-C **
10660803-T-G **
10766556-C-A **
22484676-G-A 20322790-G-A DYZ19 **
10946498-C-A **
22787263-T-C 20625377-T-C **
10807589-C-A **
10825279-C-CGGATT **
24600415-T-C 22454268-T-C FGC37396 P3_t2 **
10946867-C-A **
13450115-CCCATCCCATCCCATTCTATTCCATTCCATTCCATTCCATT-C 11294439-CCCATCCCATCCCATTCTATTCCATTCCATTCCATTCCATT-C ***
18255885-G-T 16144005-G-T ***
10848057-C-G ***
23997558-C-A 21851411-C-A ***
18188249-C-T 16076369-C-T ***
10789361-A-AT ***
13453692-C-A 11298016-C-A ***
14073169-C-A 11952463-C-A ***
10694067-C-A ***
10958365-A-ACTAAT ***
10778208-CG-C ***
15743608-G-T 13631728-G-T ***
10793238-T-C ***
10916455-A-G ***
56838749-CACTGATCA-C ***

In the table above, the meaning of the confidence field depends on whether the data comes from an FTDNA kit or an FGC kit. For FTDNA kits, + implies a "PASS" result with just one possible variant, * indicates a "PASS" but with multiple variants, ** indicates "REJECTED" with just a single variant, and *** indicates "REJECTED" with multiple possible variants. 'A*' are heterozygous variants not called by FTDNA, but still pulled from the VCF file. For FGC kits, + indicates over 99% likely genuine (95% for INDELs); * over 95% likely genuine (90% for INDELs); ** about 40% likely genuine; *** about 10% likely genuine. Manual entries read directly from a BAM file will be either + indicating positive, or * indicating that the data show a mixture of possible variants.

For the FTDNA kits, the BED data is encoded in the background color of the cells. Those cells with a white background have coverage, those with a grey background indicate no coverage in the BED file, and those with a pink background indicate the mutation is on the edge of a coverage region. These pink regions often indicate that the individual may be positive for a SNP even if there is no corresponding entry in the vcf file.

The combBED column indicates whether or not the mutation is a SNP and falls in the combBED region defined in Defining a New Rate Constant for Y-Chromosome SNPs based on Full Sequencing Data by Dmitry Adamov, Vladimir Guryanov, Sergey Karzhavin, Vladimir Tagankin, Vadim Urasin.

The McDonald BED column indicates whether or not the mutation is a SNP and falls in the BED region used by Dr. Iain McDonald in the age analysis he does for R-U106 men.

Age Analysis Information (work in progress)

AllMcDonaldYFull
Kit: 137970993816980873127952571
Used in age calculations993816980873127952571
Counts of SNPs3130
Variant counts last updated 2019-07-03 01:19:19.



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