Ruggiero

BigY3: B156745
MDKA Birth: Italy

Tree Position

R-M269 > L23 > Z2103 > Z2106 > Z2108 > Exact position not yet finalized.

Unique Mutations

The mutations unique to this man are summarized in the table below. Those with a '+' or '*' confidence level are considered by FamilyTreeDNA or FullGenomesCorp to be high quality SNPs/INDELs. For completeness, all other mutations of lesser confidence are included as well. These additional mutations may be useful for distinguishing between very closely related men.

Occasionally, some of the mutations listed here will be thought to be shared with other men in which case they might appear in upstream blocks on the tree. When this happens, the 'Blocks' field will indicate what block they appear in. Such a situation might arise with BigY men if the BED data suggests another man may be positive for a SNP, even though it doesn't appear in his VCF data. It might also happen if Chromo2 testing or Sanger sequencing of other men not on the tree show the SNP to be shared.

POS-REF-ALT (hg19) POS-REF-ALT (hg38) Blocks Names Region McDonald BED combBED STRBigY3
B156745
9535155-A-AT 9697546-A-AT IR3_Prx 17×TA+
13141895-G-C 10631381-G-C A*
20387096-G-GA 18225210-G-GA P5_Dst 11×AA*
17989950-G-A 15878070-G-A BY33254 P7_Prx YA*
22304751-T-A 20142865-T-A DYZ19 A*
58982501-A-C 56836354-A-C A*
20568537-C-A 18406651-C-A P5_Dst 27×AA*
10756579-T-C A*
10756595-A-C A*
10756608-G-T A*
10958267-G-T A*
13489465-C-A 11333789-C-A A*
10946601-C-T A*
28817452-T-C 26671305-T-C A*
20532876-G-GA 18370990-G-GA P5_Dst 11×AA*
20571031-G-GT 18409145-G-GT P5_Dst 11×TA*
20503144-A-AGGC 18341258-A-AGGC P5_Dst A*
20530790-A-ATC 18368904-A-ATC P5_Dst A*
13442790-A-T 11287114-A-T A*
16144884-C-T 14033004-C-T P8_Dst A*
16159343-A-G 14047463-A-G P8_Dst A*
18009866-G-T 15897986-G-T P7_Dst YA*
18301514-G-T 16189634-G-T P6_Prx A*
18315505-T-A 16203625-T-A P6_Prx A*
18427978-G-T 16316098-G-T P6_Dst A*
18483445-G-A 16371565-G-A P6_Dst A*
18486039-C-G 16374159-C-G P6_Dst A*
18504259-G-A 16392379-G-A P6_Dst A*
18507589-C-A 16395709-C-A P6_Dst A*
18516211-A-T 16404331-A-T P6_Dst A*
18535695-C-A 16423815-C-A P6_Dst A*
20077135-C-A 17965255-C-A P5_Dst A*
20122783-G-T 18010903-G-T P5_Dst A*
20231488-T-A 18069602-T-A P5_Dst A*
20250269-C-T 18088383-C-T P5_Dst A*
20305503-A-G 18143617-A-G P5_Dst A*
20324363-C-T 18162477-C-T P5_Dst A*
20334519-C-T 18172633-C-T P5_Dst A*
20336019-T-C 18174133-T-C P5_Dst A*
20341268-C-T 18179382-C-T P5_Dst A*
20346051-G-A 18184165-G-A P5_Dst A*
20350451-C-CA 18188565-C-CA P5_Dst 27×AA*
20364335-C-A 18202449-C-A P5_Dst A*
20378880-G-A 18216994-G-A P5_Dst A*
20398160-C-T 18236274-C-T P5_Dst A*
20419761-T-C 18257875-T-C P5_Dst A*
20430086-G-A 18268200-G-A P5_Dst A*
20445717-C-T 18283831-C-T P5_Dst A*
20453290-T-C 18291404-T-C P5_Dst A*
20457030-A-C 18295144-A-C P5_Dst A*
20481465-A-G 18319579-A-G P5_Dst A*
20487301-A-G 18325415-A-G P5_Dst A*
20503271-G-A 18341385-G-A P5_Dst A*
20528557-A-G 18366671-A-G P5_Dst A*
20532550-C-T 18370664-C-T P5_Dst A*
20549044-G-T 18387158-G-T P5_Dst A*
20579685-A-G 18417799-A-G P5_Dst A*
20726038-T-G 18564152-T-G P4_Prx A*
20749383-T-C 18587497-T-C P4_Prx A*
20869294-T-C 18707408-T-C P4_Dst A*
20894792-A-G 18732906-A-G P4_Dst A*
20918137-A-C 18756251-A-C P4_Dst A*
20944551-T-C 18782665-T-C P4_Dst A*
20994191-A-G 18832305-A-G P4_Dst A*
20997841-T-C 18835955-T-C P4_Dst YA*
21011841-A-G 18849955-A-G P4_Dst YA*
21013084-A-ATT 18851198-A-ATT P4_Dst 14×TA*
22231885-A-G 20069999-A-G DYZ19 A*
22319377-C-T 20157491-C-T DYZ19 A*
25981559-C-G 23835412-C-G P1_Y1 A*
26151527-G-A 24005380-G-A P1_Y1 A*
26328541-C-A 24182394-C-A P1_Y1 A*
26453788-A-G 24307641-A-G P1_Y1 A*
56833765-C-T A*
56834176-T-C A*
21834863-A-T 19672977-A-T CTS750Z16369 FGC13408 Y+
28732049-C-T 26585902-C-T PR7597 FT77669 Y+
14271263-C-CT 12150557-C-CT Y2538 8×T+
15386959-G-A 13275079-G-A FT22004 YY+
21269484-A-C 19107598-A-C A10987M9313 Y+
22460636-T-A 20298750-T-A DYZ19 +
28627740-C-T 26481593-C-T Z32415 +
6780570-C-A 6912529-C-A FT18751 YY+
19197710-G-T 17085830-G-T BY127140 YY+
3855208-G-A 3987167-G-A FT15784 +
4061151-G-A 4193110-G-A FT16023 +
4498023-C-T 4629982-C-T FT16546 +
4567539-T-C 4699498-T-C FT16630 +
4743047-C-G 4875006-C-G FT16811 +
4798160-G-T 4930119-G-T FT16860 +
5184368-T-A 5316327-T-A FT17281 +
6000173-T-A 6132132-T-A FT18251 +
6480702-C-A 6612661-C-A FT18529 +
6524493-C-G 6656452-C-G FT18580 +
6983306-G-C 7115265-G-C FT18868 YY+
7616684-C-T 7748643-C-T YY+
7892317-T-A 8024276-T-A FT19506 YY+
8070576-G-C 8202535-G-C FT19623 YY+
8649989-A-C 8781948-A-C YY+
9170615-C-T 9333006-C-T FT20362 Y+
9776787-A-C 9939178-A-C FT20528 Y+
13196118-C-G 11040442-C-G BY84242 +
13229664-G-C 11073988-G-C +
13585333-G-A 11429657-G-A BY86517 +
13620492-A-T 11464816-A-T FT446586 +
14278011-A-G 12157305-A-G BY94518 YY+
14864377-T-C 12752443-T-C FT21659 YY+
15734831-G-A 13622951-G-A FT22232 YY+
15966117-C-T 13854237-C-T FT22390 YY+
16201991-C-T 14090111-C-T YY+
16645783-G-A 14533903-G-A FT22891 YY+
17181423-G-A 15069543-G-A FT23275 YY+
17616197-G-A 15504317-G-A BY116200 YY+
17773439-T-A 15661559-T-A BY117337 YY+
18100677-G-A 15988797-G-A FT24060 YY+
18997870-T-C 16885990-T-C FT24592 YY+
21123585-GCCCGTATAC-G 18961699-GCCCGTATAC-G +
21405838-A-T 19243952-A-T FT25340 YY+
21556195-TTTACAGTTGACA-T 19394309-TTTACAGTTGACA-T +
21726398-T-A 19564512-T-A BY135022 YY+
22745438-G-A 20583552-G-A FT26134 YY+
28554665-C-T 26408518-C-T FT27123 +
13463231-A-G,T 11307555-A-G,T *
22046265-AAAC-A 19884379-AAAC-A 11×AAC*
9640889-TTGTGTG-T 9803280-TTGTGTG-T IR3_Prx 22×TG*
9468134-T-TTG 9630525-T-TTG 17×TG*
22189234-C-CA 20027348-C-CA 17×A*
13452673-T-G 11296997-T-G *
13452710-C-G 11297034-C-G *
23773323-T-TAC 21611437-T-TAC 24×AC*
16242402-C-CT 14130522-C-CT 18×T*
10987189-T-C *
6983589-CTGTGTG-C 7115548-CTGTGTG-C 20×TG*
2802805-C-CT 2934764-C-CT 15×T*
11012297-G-GCATTC *
16749739-T-G 14637859-T-G FT296992 YY*
16749738-T-G 14637858-T-G YY*
4032759-A-T 4164718-A-T FGC54420 *
5563117-T-TACAC 5695076-T-TACAC 16×AC*
2919142-T-C 3051101-T-C *
9398507-C-CA 9560898-C-CA *
4964910-A-AT 5096869-A-AT 15×T**
6523251-T-C 6655210-T-C FGC33476FGC3 AD0000010 **
4336555-AAT-A 4468514-AAT-A 9×AT**
18801261-GTA-G 16689381-GTA-G 9×TA**
13455580-A-T 11299904-A-T **
13446804-GCCATTCCATTCCATTCCATTCCATTCCATTCCATTCCATTCCATTCCATT-G 11291128-GCCATTCCATTCCATTCCATTCCATTCCATTCCATTCCATTCCATTCCATT-G 12×CCATT**
13481407-A-G 11325731-A-G **
21747763-G-A FT270897 **
8724374-ATATACATGTG-A 8856333-ATATACATGTG-A **
10526-A-T **
13611830-CTTT-C 11456154-CTTT-C 23×T**
9340754-C-A 9503145-C-A **
13214882-C-A 11059206-C-A **
13455575-A-ACCCTGTTTGT 11299899-A-ACCCTGTTTGT **
13613602-C-T 11457926-C-T **
15324902-G-C 13213020-G-C **
15636333-G-T 13524453-G-T **
21697726-G-T 19535840-G-T **
22235825-G-A 20073939-G-A BY52130 DYZ19 **
24166-A-T **
4270959-AAGAT-A 4402918-AAGAT-A 15×AGAT***
15848962-TTATA-T 13737082-TTATA-T 13×TA***
2809540-A-AT 2941499-A-AT 18×T***
9521986-A-ATATC 9684377-A-ATATC 12×TATC***
3374847-CAA-C 3506806-CAA-C 23×A***
19138084-C-CTA 17026204-C-CTA 10×TA***
14031744-TTCTTTC-T 11911038-TTCTTTC-T ***
6150009-G-A 6281968-G-A A3687 IR3_Dst 19×TA***
10020521-G-C 10182912-G-C ***
16297330-GTT-G 14185450-GTT-G 26×T***
4064345-T-TA 4196304-T-TA 11×A***
17054917-A-G 14943037-A-G ZS2465 ***
19187385-ATT-A,AT 17075505-ATT-A,AT 28×T***
15951900-T-TTG 13840020-T-TTG 13×TG***
22829644-CAA-C 20667758-CAA-C 18×A***
28529232-CAA-C 26383085-CAA-C 23×A***
4521322-T-TA 4653281-T-TA 15×A***
13608647-CAAAA-C 11452971-CAAAA-C 27×A***
16990223-CA-C 14878343-CA-C 24×A***
15468678-CAA-C 13356798-CAA-C 23×A***
21464771-GTTCTTCTTC-G 19302885-GTTCTTCTTC-G 16×TTC***
14020334-TA-T 11899628-TA-T 10×A***
3990664-CAA-C 4122623-CAA-C 18×A***
13487375-G-T 11331699-G-T ***
16336897-GTTTTT-G 14225017-GTTTTT-G 23×T***
21099740-CTTTT-C 18937854-CTTTT-C 16×T***
10987197-C-A ***
13997771-C-CT 11877065-C-CT 17×T***
10670988-TTCTTTTCCAC-T,TTCTATTCCAC ***
25592900-CTATA-C 23446753-CTATA-C P1_gr1 12×TA***
13480391-A-T 11324715-A-T ***
13480392-C-G 11324716-C-G ***
10748250-A-ACCATT ***
18395599-CAAA-C 16283719-CAAA-C P6_Gap 15×A***
21149582-GTT-G 18987696-GTT-G 27×T***
24485675-CT-C 22339528-CT-C 15×T***
13480368-T-C 11324692-T-C ***
13480383-C-A 11324707-C-A ***
13480393-C-A,G 11324717-C-A,G ***
13452389-TTCCAT-T,TTCCAG 11296713-TTCCAT-T,TTCCAG ***
13485557-G-C 11329881-G-C ***
7567753-CTTT-C 7699712-CTTT-C 25×T***
18593205-C-CT 16481325-C-CT 10×T***
11036116-ACTCTT-A ***
13695219-C-CG 11539543-C-CG ***
17703235-C-A 15591355-C-A ***
13909304-CAAAA-C 11788598-CAAAA-C 18×A***
2812777-ATTTT-A 2944736-ATTTT-A 30×T***
4301306-T-TA 4433265-T-TA 12×A***
10801731-CCTTTT-C ***
6648613-CTTTT-C 6780572-CTTTT-C 27×T***
8333626-ACTTCTTCTTCTTCTT-A 8465585-ACTTCTTCTTCTTCTT-A 25×CTT***
7076612-CAAAAAAAAAAA-C 7208571-CAAAAAAAAAAA-C 29×A***
28793764-T-A 26647617-T-A ***
5480908-CTT-C 5612867-CTT-C 16×T***
17186726-TAAAA-T,TAA 15074846-TAAAA-T,TAA 19×A***
4375417-CTT-C 4507376-CTT-C 22×T***
4669265-ATT-A 4801224-ATT-A 15×T***
3174374-CTT-C 3306333-CTT-C 18×T***
28812997-C-G 26666850-C-G ***
7135386-ATTT-A,ATT 7267345-ATTT-A,ATT 22×T***
10673941-TGCACC-T,TCCATTGCACC ***
5388277-AAA-A,AT 5520236-AAA-A,AT ***
7220911-AAAAC-A 7352870-AAAAC-A 4×AAAC***
7269610-CTTTT-C,CTTT 7401569-CTTTT-C,CTTT 22×T***
13340036-A-C 11184360-A-C ***
13363384-C-T 11207708-C-T ***
15174560-T-A 13062646-T-A ***
22227379-A-G 20065493-A-G DYZ19 ***
22430242-G-C 20268356-G-C DYZ19 ***
23007965-T-A 20846079-T-A ***
28534940-CT-C,CTT 26388793-CT-C,CTT 18×T***
56862621-CTTTT-C,CTTTTTTT 14×T***

In the table above, the meaning of the confidence field depends on whether the data comes from an FTDNA kit or an FGC kit. For FTDNA kits, + implies a "PASS" result with just one possible variant, * indicates a "PASS" but with multiple variants, ** indicates "REJECTED" with just a single variant, and *** indicates "REJECTED" with multiple possible variants. 'A*' are heterozygous variants not called by FTDNA, but still pulled from the VCF file. For FGC kits, + indicates over 99% likely genuine (95% for INDELs); * over 95% likely genuine (90% for INDELs); ** about 40% likely genuine; *** about 10% likely genuine. Manual entries read directly from a BAM file will be either + indicating positive, or * indicating that the data show a mixture of possible variants.

For the FTDNA kits, the BED data is encoded in the background color of the cells. Those cells with a white background have coverage, those with a grey background indicate no coverage in the BED file, and those with a pink background indicate the mutation is on the edge of a coverage region. These pink regions often indicate that the individual may be positive for a SNP even if there is no corresponding entry in the vcf file.

The combBED column indicates whether or not the mutation is a SNP and falls in the combBED region defined in Defining a New Rate Constant for Y-Chromosome SNPs based on Full Sequencing Data by Dmitry Adamov, Vladimir Guryanov, Sergey Karzhavin, Vladimir Tagankin, Vadim Urasin.

The McDonald BED column indicates whether or not the mutation is a SNP and falls in the BED region used by Dr. Iain McDonald in the age analysis he does for R-U106 men.