Donoghue

BigY3: 10511, BigY2: 10511
MDKA Birth: Ireland

Tree Position

R-P312/S116 > Z290 > L21/S145 > S552 > DF13 > ZZ10 > Z253 > BY4086 > FGC17436 > Z17693 > FGC73657 > A505 > S7897 > A495 > S7898 > S15280 > ~18618565-G-A

Unique Mutations

The mutations unique to this man are summarized in the table below. Those with a '+' or '*' confidence level are considered by FamilyTreeDNA or FullGenomesCorp to be high quality SNPs/INDELs. For completeness, all other mutations of lesser confidence are included as well. These additional mutations may be useful for distinguishing between very closely related men.

Occasionally, some of the mutations listed here will be thought to be shared with other men in which case they might appear in upstream blocks on the tree. When this happens, the 'Blocks' field will indicate what block they appear in. Such a situation might arise with BigY men if the BED data suggests another man may be positive for a SNP, even though it doesn't appear in his VCF data. It might also happen if Chromo2 testing or Sanger sequencing of other men not on the tree show the SNP to be shared.

POS-REF-ALT (hg19) POS-REF-ALT (hg38) Blocks Names Region McDonald BED combBED STRBigY3
10511		BigY2
10511
4414831-T-G 4546790-T-G A+
28060324-G-A 25914177-G-A P1_Y2 A+
9540246-C-CT 9702637-C-CT IR3_Prx 18×TA*
24607773-C-CAA 22461626-C-CAA P3_t2 19×AA*
25882922-A-G 23736775-A-G P1_Y1 A*A*
13449564-C-G 11293888-C-G A*
13489645-G-A 11333969-G-A A*
19635464-C-T 17523584-C-T P5_Prx A*
19659412-C-T 17547532-C-T P5_Prx A*
19940418-A-G 17828538-A-G P5_Prx A*
20406117-C-T 18244231-C-T P5_Dst A*
20798432-T-C 18636546-T-C P4_Prx A*
26041432-G-C 23895285-G-C P1_Y1 A*
21845600-C-CA 19683714-C-CA 9×A***+
17572094-C-T 15460214-C-T FT85096 YY+
18672379-TTTTATTTA-T 16560499-TTTTATTTA-T 8×TTTA+**
2715633-A-G 2847592-A-G BY186177 YY++
4133975-C-T 4265934-C-T FT84440 +**
6810755-C-G 6942714-C-G BY186301 YY++
7795661-G-A 7927620-G-A BY186492 YY++
8040004-A-G 8171963-A-G BY186558 YY++
9390074-G-T 9552465-G-T BY186849 Y++
9796437-G-C 9958828-G-C BY186910 Y++
10009308-G-A 10171699-G-A BY209575 Y++
14823072-A-T 12711139-A-T BY187157 YY++
15549581-T-C 13437701-T-C BY187297 YY++
16184601-C-T 14072721-C-T BY105807 Y++
17531602-C-T 15419722-C-T BY187662 YY++
18708519-T-C 16596639-T-C YY+**
18765007-C-T 16653127-C-T FT85143 YY+**
21785144-G-C 19623258-G-C BY188243 YY++
22892014-TG-T 20730128-TG-T ++
23055977-A-T 20894091-A-T FT85254 YY+**
23115998-T-G 20954112-T-G BY188541 YY++
5615990-T-G 5747949-T-G FT84681 +
10811781-C-T FT387204 +
21831139-T-G 19669253-T-G FT85215 Y+
13451745-ACTCCATTCCACTCCG-A,AATCCATTCCATTCCG 11296069-ACTCCATTCCACTCCG-A,AATCCATTCCATTCCG *
13449753-CAACCC-CAA,T 11294077-CAACCC-CAA,T *
13457510-C-T 11301834-C-T **
13848304-A-G 11727598-A-G DYZ17 **
17576243-GAAA-G 15464363-GAAA-G 16×A**
5225276-GTA-G 5357235-GTA-G **
19528943-A-AT 17417063-A-AT Y1963 **
22442516-G-T 20280630-G-T ZS7869 DYZ19 **
20510927-G-T 18349041-G-T P5_Dst **
18340487-CAT-C 16228607-CAT-C P6_Prx **
7154570-C-A 7286529-C-A **
5976652-C-A 6108611-C-A **
10746938-TGTTCC-T **
14586331-C-A 12474531-C-A **
10987785-A-T **
56832556-C-A **
6210422-G-T 6342381-G-T IR3_Dst **
25994029-A-G 23847882-A-G P1_Y1 **
23205080-C-A 21043194-C-A **
10958306-A-C **
11643746-A-G DYZ17 **
18443407-C-A 16331527-C-A P6_Dst **
4081010-C-A 4212969-C-A **
4017009-C-A 4148968-C-A **
8720236-C-A 8852195-C-A **
10744241-C-CTACTCCATCA **
18892136-C-A 16780256-C-A **
15405272-C-A 13293392-C-A **
10759977-T-G **
15740493-C-A 13628613-C-A **
7052915-C-A 7184874-C-A **
14300630-C-A 12179924-C-A **
18138085-C-A 16026205-C-A **
19129538-C-A 17017658-C-A **
16823828-C-A 14711948-C-A **
18965106-C-A 16853226-C-A **
23352341-T-C 21190455-T-C **
10661643-C-A **
28784448-G-T 26638301-G-T **
23044729-C-A 20882843-C-A **
10937807-T-C **
13457436-TCATTC-T 11301760-TCATTC-T 4×CATTC**
11014472-C-T **
15969862-C-A 13857982-C-A **
18539043-C-A 16427163-C-A **
24148074-C-A 22001927-C-A P3_b1 **
15495397-C-A 13383517-C-A **
22205049-G-T 20043163-G-T **
10925960-T-C **
14558481-C-A 12446682-C-A **
14657551-C-A 12545616-C-A **
10937802-T-C **
18145625-C-A 16033745-C-A **
23609562-C-A 21447676-C-A **
13639821-C-A 11484145-C-A **
26224808-TA-T 24078661-TA-T P1_Y1 **
16015529-C-A 13903649-C-A **
22181824-C-A 20019938-C-A **
5796750-C-A 5928709-C-A **
15364487-C-A 13252607-C-A **
15722710-C-A 13610830-C-A **
22993397-C-A 20831511-C-A **
22703519-C-A 20541633-C-A **
10661593-C-A **
7083071-C-A 7215030-C-A **
7304331-C-A 7436290-C-A **
17130481-C-A 15018601-C-A **
27860907-A-C 25714760-A-C P1_Y2 **
6347619-G-T 6479578-G-T **
4293518-C-A 4425477-C-A **
14563528-C-A 12451728-C-A **
21558721-C-A 19396835-C-A **
18825686-C-A 16713806-C-A **
13961818-C-A 11841112-C-A **
15099-CTTTCAGATG-C **
7431696-A-G 7563655-A-G **
10925953-T-C **
10925955-C-T FT436781 **
10925973-C-T **
10925978-C-T **
9109354-G-T **
19930428-G-T 17818548-G-T P5_Prx **
16528131-T-G 14416251-T-G **
27918819-A-AG 25772672-A-AG P1_Y2 **
10033285-C-T 10195676-C-T **
15584469-C-A 13472589-C-A **
15321309-C-A 13209427-C-A **
21154578-C-A 18992692-C-A **
16827661-AT-A 14715781-AT-A 9×T**
27540965-CAG-C 25394818-CAG-C P1_Y2 **
23440218-G-T 21278332-G-T **
17645637-C-A 15533757-C-A **
6755786-T-G 6887745-T-G **
9307457-T-A 9469848-T-A **
10925970-C-G **
13222282-G-A 11066606-G-A **
28698539-C-A 26552392-C-A **
11001927-C-A **
9636060-T-TC 9798451-T-TC IR3_Prx **
13883164-C-A 11762458-C-A **
10958288-C-G **
7409535-C-A 7541494-C-A **
9077070-G-T 9239461-G-T **
56884367-G-T **
18158509-C-A 16046629-C-A **
13952751-C-A 11832045-C-A **
18867339-CTTTTTTT-C 16755459-CTTTTTTT-C 24×T**
27902167-A-T 25756020-A-T P1_Y2 **
16719990-C-A 14608110-C-A **
7706538-C-A 7838497-C-A **
22513179-C-A 20351293-C-A **
14574129-C-A 12462329-C-A **
14953387-C-A 12841461-C-A **
10083613-A-T 10246004-A-T **
15593302-G-T 13481422-G-T **
21945356-C-A 19783470-C-A **
3847097-C-A 3979056-C-A **
19431508-C-A 17319628-C-A **
13945440-T-G 11824734-T-G **
56832350-C-A **
2775544-C-A 2907503-C-A **
2811353-A-G 2943312-A-G **
2845221-CAAAAAAAAAAAAAAAAAA-C 2977180-CAAAAAAAAAAAAAAAAAA-C 38×A**
3286020-AT-A 3417979-AT-A **
3418570-G-T 3550529-G-T **
3627963-G-A 3759922-G-A **
4223465-C-A 4355424-C-A **
4585567-C-A 4717526-C-A **
4703581-C-A 4835540-C-A **
5199924-T-G 5331883-T-G **
5249201-C-A 5381160-C-A **
6001324-C-A 6133283-C-A **
6132093-C-A 6264052-C-A **
6420393-G-T 6552352-G-T **
6512333-C-A 6644292-C-A **
6768926-C-G 6900885-C-G **
7088505-C-A 7220464-C-A **
7115836-T-C 7247795-T-C **
7225468-A-G 7357427-A-G **
7382397-T-C 7514356-T-C **
7382398-G-A 7514357-G-A **
7382412-A-C 7514371-A-C **
7645505-G-A 7777464-G-A **
8056167-G-T 8188126-G-T **
9776149-C-A 9938540-C-A **
10036047-A-G 10198438-A-G **
10828398-ACTCC-A **
10958305-A-T **
10958354-C-T **
13222362-A-G 11066686-A-G **
13254525-A-AGTGTC 11098849-A-AGTGTC **
13254528-AC-A 11098852-AC-A **
13278577-C-A 11122901-C-A **
13289982-C-A 11134306-C-A **
13328871-C-T 11173195-C-T **
13488492-C-A 11332816-C-A **
13551075-T-G 11395399-T-G **
13602877-C-A 11447201-C-A **
13895765-C-A 11775059-C-A **
13934384-T-G 11813678-T-G **
13942303-C-A 11821597-C-A **
13945438-A-C 11824732-A-C **
13999595-G-T 11878889-G-T **
14105334-G-A 11984628-G-A **
14147769-T-G 12027063-T-G **
14219620-C-A 12098914-C-A **
14293818-C-A 12173112-C-A **
14359729-C-A 12239024-C-A **
14392848-C-A 12272144-C-A **
14586231-C-A 12474431-C-A **
14591906-C-A 12480106-C-A BY169961 **
14629716-C-CT 12517785-C-CT **
14749126-G-A 12637195-G-A **
14846918-T-C 12734984-T-C **
14871476-A-G 12759546-A-G **
15011160-C-A 12899245-C-A **
15449851-A-T 13337971-A-T **
15653589-C-A 13541709-C-A **
15690062-G-A 13578182-G-A FT23799 **
15742913-A-T 13631033-A-T **
15811347-C-A 13699467-C-A **
15995061-C-A 13883181-C-A **
16016986-C-A 13905106-C-A **
16018972-G-A 13907092-G-A **
16429619-C-T 14317739-C-T FGC26668 **
16827535-G-C 14715655-G-C **
16834112-C-A 14722232-C-A **
17146606-C-A 15034726-C-A **
17714118-T-C 15602238-T-C **
17884521-A-G 15772641-A-G **
17927496-C-A 15815616-C-A **
17955961-T-G 15844081-T-G **
18078130-T-C 15966250-T-C **
18090195-C-T 15978315-C-T **
18412934-A-G 16301054-A-G P6_Gap **
18564306-C-A 16452426-C-A **
18687486-A-G 16575606-A-G **
18739715-C-A 16627835-C-A **
18850727-T-A 16738847-T-A **
19112487-C-T 17000607-C-T **
19787942-C-A 17676062-C-A P5_Prx **
19878779-G-T 17766899-G-T P5_Prx **
20340094-C-T 18178208-C-T P5_Dst **
20489480-A-G 18327594-A-G P5_Dst **
21141479-C-A 18979593-C-A **
21219802-C-G 19057916-C-G **
21472357-C-A 19310471-C-A **
21512393-C-A 19350507-C-A **
21700363-G-A 19538477-G-A **
21905340-C-A 19743454-C-A **
22079880-C-A 19917994-C-A **
22442511-A-T 20280625-A-T DYZ19 **
22528382-A-C 20366496-A-C **
22880893-C-A 20719007-C-A **
22993506-A-G 20831620-A-G **
23020000-C-A 20858114-C-A **
23042301-A-G 20880415-A-G **
23059604-T-C 20897718-T-C **
23098172-C-A 20936286-C-A **
23306394-C-A 21144508-C-A **
23452585-G-A 21290699-G-A **
23651157-A-G 21489271-A-G **
23825621-G-T 21663735-G-T **
23837437-G-T 21675551-G-T **
24369470-C-A 22223323-C-A **
24378993-C-A 22232846-C-A **
24874285-A-C 22728138-A-C g1 **
25913872-G-A 23767725-G-A P1_Y1 **
25993405-A-T 23847258-A-T P1_Y1 **
26064232-T-A 23918085-T-A P1_Y1 **
26084920-A-G 23938773-A-G P1_Y1 **
26170488-A-AGAT 24024341-A-AGAT P1_Y1 **
27647692-G-T 25501545-G-T P1_Y2 **
27860920-G-T 25714773-G-T P1_Y2 **
28479739-C-A 26333592-C-A **
28484870-C-T 26338723-C-T **
28546905-C-A 26400758-C-A **
28602493-C-A 26456346-C-A **
28621387-G-T 26475240-G-T **
28804429-G-C 26658282-G-C **
56832474-C-A **
56835673-T-A **
21013085-T-TA 18851199-T-TA P4_Dst **
3460953-C-G 3592912-C-G **
14086987-T-C 11966281-T-C **
16119962-T-C 14008082-T-C P8_Prx **
16119963-C-CTGT 14008083-C-CTGT P8_Prx **
16119969-TTC-T 14008089-TTC-T P8_Prx **
17540760-A-C 15428880-A-C **
17839581-G-A 15727701-G-A **
20333897-C-A 18172011-C-A P5_Dst **
20581782-ATTTT-A 18419896-ATTTT-A P5_Dst 17×T**
22580096-G-A 20418210-G-A **
23898957-T-A 21737071-T-A **
24568397-A-ATT 22422250-A-ATT P3_t2 **
26344088-C-CA 24197941-C-CA P1_Y1 8×A**
56852791-T-C **
3640682-CTCCTTCCTTCCT-C 3772641-CTCCTTCCTTCCT-C 14×TCCT***
15918217-A-AT 13806337-A-AT 10×T***
21153008-GA-G 18991122-GA-G 8×A***
14748053-C-T 12636122-C-T ***
5179539-TATAC-T 5311498-TATAC-T ***
7269610-CTTTTTT-C 7401569-CTTTTTT-C 22×T***
17047880-ATTTT-A 14936000-ATTTT-A 16×T***
8677873-C-A 8809832-C-A BY232FGC72908 Y87704 ***
18565591-ATT-A 16453711-ATT-A 15×T***
2892542-AT-A,ATT 3024501-AT-A,ATT 18×T***
22173846-C-A 20011960-C-A ***
18108457-CTTT-C 15996577-CTTT-C 13×T***
13811138-G-T 11690432-G-T DYZ17 ***
17312731-C-CT 15200851-C-CT 9×T***
22521626-C-A 20359740-C-A ***
28763651-C-A 26617504-C-A ***
14784701-CTTTTTTT-C 12672771-CTTTTTTT-C 22×T***
19401599-TAA-T 17289719-TAA-T 11×A***
22768348-TAAA-T 20606462-TAAA-T 17×A***
19536953-C-A 17425073-C-A ***
23002319-CTTT-C,CT 20840433-CTTT-C,CT 14×T***
13545835-AG-A 11390159-AG-A ***
7418073-CAAAAAAA-C 7550032-CAAAAAAA-C 22×A***
14729762-C-A 12617830-C-A ***
13989943-C-A 11869237-C-A ***
8182205-CAAAAAAA-C 8314164-CAAAAAAA-C 18×A***
19517491-C-A 17405611-C-A ***
13530079-CAAAA-C 11374403-CAAAA-C 24×A***
18717876-TAA-T,TAAA 16605996-TAA-T,TAAA 16×A***
5986669-T-G 6118628-T-G ***
20812513-C-A 18650627-C-A P4_Gap ***
14264364-C-A 12143658-C-A ***
21547373-C-A 19385487-C-A ***
2717283-A-G 2849242-A-G ***
3716979-C-A 3848938-C-A ***
6523291-C-A 6655250-C-A ***
7339978-A-G 7471937-A-G ***
7387344-C-A 7519303-C-A ***
7603093-G-A 7735052-G-A ***
8081022-C-A 8212981-C-A ***
8106729-C-A 8238688-C-A ***
8452192-CAA-C,CAAAA 8584151-CAA-C,CAAAA 15×A***
11014384-CT-C ***
13288716-C-A 11133040-C-A ***
13471648-C-A 11315972-C-A ***
13473845-A-C 11318169-A-C ***
14370746-G-A 12250042-G-A ***
14590089-A-G 12478289-A-G ***
14656487-T-C 12544552-T-C ***
14816711-A-G 12704782-A-G ***
15011392-G-A 12899480-G-A ***
15052292-C-A 12940383-C-A ***
15057738-ATTTT-A,ATT 12945830-ATTTT-A,ATT 18×T***
15850824-T-C 13738944-T-C ***
16519316-CAAAA-C,CAA 14407436-CAAAA-C,CAA 15×A***
16666336-C-A 14554456-C-A ***
16901108-C-A 14789228-C-A ***
17137226-C-A 15025346-C-A ***
17234344-C-A 15122464-C-A ***
17278273-CGAAAGAAAGAAAGAAA-C,CGAAA 15166393-CGAAAGAAAGAAAGAAA-C,CGAAA 16×GAAA***
17489615-G-A 15377735-G-A ***
17596697-T-C 15484817-T-C ***
17631083-G-A 15519203-G-A ***
18593128-A-G 16481248-A-G ***
18762450-T-C 16650570-T-C ***
19122366-T-C 17010486-T-C ***
19284138-G-A 17172258-G-A ***
19493928-C-A 17382048-C-A ***
21228455-A-G 19066569-A-G ***
21295201-C-A 19133315-C-A ***
21444332-C-A 19282446-C-A ***
21469225-C-A 19307339-C-A ***
21751519-G-A 19589633-G-A ***
21809524-C-A 19647638-C-A ***
22030034-G-A 19868148-G-A ***
22685397-C-A 20523511-C-A ***
23351677-C-A 21189791-C-A ***
24378786-A-G 22232639-A-G ***
27862578-G-C 25716431-G-C P1_Y2 ***
4678058-G-GT,GTT 4810017-G-GT,GTT 15×T***
6727643-G-A 6859602-G-A ***
7098943-G-C 7230902-G-C ***
9025120-C-T 9187511-C-T ***
10985201-C-CTCCAT ***
13588028-C-T 11432352-C-T ***
13898348-G-T 11777642-G-T ***
15932040-A-G 13820160-A-G ***
21574183-T-A 19412297-T-A ***
22774869-CTTT-C,CTTTT 20612983-CTTT-C,CTTTT 21×T***
25803203-G-T 23657056-G-T P1_b3 ***

In the table above, the meaning of the confidence field depends on whether the data comes from an FTDNA kit or an FGC kit. For FTDNA kits, + implies a "PASS" result with just one possible variant, * indicates a "PASS" but with multiple variants, ** indicates "REJECTED" with just a single variant, and *** indicates "REJECTED" with multiple possible variants. 'A*' are heterozygous variants not called by FTDNA, but still pulled from the VCF file. For FGC kits, + indicates over 99% likely genuine (95% for INDELs); * over 95% likely genuine (90% for INDELs); ** about 40% likely genuine; *** about 10% likely genuine. Manual entries read directly from a BAM file will be either + indicating positive, or * indicating that the data show a mixture of possible variants.

For the FTDNA kits, the BED data is encoded in the background color of the cells. Those cells with a white background have coverage, those with a grey background indicate no coverage in the BED file, and those with a pink background indicate the mutation is on the edge of a coverage region. These pink regions often indicate that the individual may be positive for a SNP even if there is no corresponding entry in the vcf file.

The combBED column indicates whether or not the mutation is a SNP and falls in the combBED region defined in Defining a New Rate Constant for Y-Chromosome SNPs based on Full Sequencing Data by Dmitry Adamov, Vladimir Guryanov, Sergey Karzhavin, Vladimir Tagankin, Vadim Urasin.

The McDonald BED column indicates whether or not the mutation is a SNP and falls in the BED region used by Dr. Iain McDonald in the age analysis he does for R-U106 men.