Herschler

BigY2: 717428
MDKA Birth: Germany

Tree Position

R-P312/S116 > Z40481 > ZZ11 > DF27/S250 > Z195/S355 > Z272 > S450 > Z295/S1217 > S25783 > CTS4065 > 15548847GACAC-G > FGC15710 > CTS10029 > BY3190

Unique Mutations

The mutations unique to this man are summarized in the table below. Those with a '+' or '*' confidence level are considered by FamilyTreeDNA or FullGenomesCorp to be high quality SNPs/INDELs. For completeness, all other mutations of lesser confidence are included as well. These additional mutations may be useful for distinguishing between very closely related men.

Occasionally, some of the mutations listed here will be thought to be shared with other men in which case they might appear in upstream blocks on the tree. When this happens, the 'Blocks' field will indicate what block they appear in. Such a situation might arise with BigY men if the BED data suggests another man may be positive for a SNP, even though it doesn't appear in his VCF data. It might also happen if Chromo2 testing or Sanger sequencing of other men not on the tree show the SNP to be shared.

POS-REF-ALT (hg19) POS-REF-ALT (hg38) Blocks Names Region McDonald BED combBED STRBigY2
717428
18518976-T-C 16407096-T-C FGC1513 Y4989 P6_Dst A*
19600428-A-G 17488548-A-G ZS10022 P5_Prx YA*
10964813-A-T A*
10769918-G-A A*
6230974-T-C 6362933-T-C IR3_Dst A*
19867547-T-C 17755667-T-C P5_Prx A*
19932908-T-C 17821028-T-C P5_Prx A*
26023404-G-C 23877257-G-C P1_Y1 A*
15211457-C-T 13099543-C-T BY206922 YY+
21463525-AAAAC-A 19301639-AAAAC-A 4×AAAC+
7923476-A-G 8055435-A-G BY205966 YY+
8068384-C-G 8200343-C-G BY206014 YY+
8159855-T-A 8291814-T-A BY206048 YY+
8483578-T-C 8615537-T-C BY206176 YY+
8736223-C-T 8868182-C-T BY206258 Y+
8998493-C-T 9160884-C-T BY77157 Y+
9044323-A-G 9206714-A-G BY206330 Y+
9147389-G-T 9309780-G-T BY206351 Y+
14078667-G-A 11957961-G-A BY206593 YY+
14208062-TA-T 12087356-TA-T +
14231828-C-T 12111122-C-T BY206664 YY+
14338381-G-C 12217676-G-C BY206702 YY+
15037597-G-A 12925685-G-A FT76370 YY+
15264076-C-T 13152166-C-T BY206936 YY+
15265237-G-C 13153326-G-C BY206937 YY+
15461973-CAA-C 13350093-CAA-C +
16768406-G-T 14656526-G-T BY207319 YY+
17581042-G-A 15469162-G-A BY207568 YY+
17597077-T-C 15485197-T-C BY207571 YY+
17644727-C-T 15532847-C-T BY207577 YY+
18061397-A-G 15949517-A-G BY207701 YY+
19318452-G-C 17206572-G-C BY208039 YY+
19453465-A-C 17341585-A-C BY208089 YY+
21355963-C-T 19194077-C-T BY208214 YY+
21796850-CT-C 19634964-CT-C +
21796853-GCCTGGA-G 19634967-GCCTGGA-G +
22458565-G-A 20296679-G-A BY220143 DYZ19 +
23450231-G-C 21288345-G-C BY208844 YY+
23838990-GGCTCCCACAGT-G 21677104-GGCTCCCACAGT-G +
22253284-G-T 20091398-G-T DYZ19 *
22314316-G-C 20152430-G-C DYZ19 *
26199599-TTA-T 24053452-TTA-T P1_Y1 **
10684291-C-T **
28798300-T-A 26652153-T-A **
6807928-C-A 6939887-C-A **
15342653-T-A 13230772-T-A FT5374 11×A**
22203898-G-T 20042012-G-T **
10671396-T-A **
10671399-A-C **
10671404-T-A **
14926326-A-G 12814391-A-G **
14926335-C-T 12814400-C-T **
10947345-C-T **
10851809-TTTCCA-T **
56846025-G-T **
13453226-ATCCATTCCAT-A 11297550-ATCCATTCCAT-A 10×TCCAT**
10669389-C-G **
27462006-G-T 25315859-G-T P1_Y2 **
10660741-T-TTTCCA **
11032174-C-A **
27861875-CAAAAAAAA-C 25715728-CAAAAAAAA-C P1_Y2 32×A**
11031343-C-A **
10884924-T-G **
10943121-C-A **
28414136-CT-C 26267989-CT-C P1_gr2 8×T**
10880344-T-G **
56742698-A-T **
11006498-T-C **
18086336-C-A 15974456-C-A Y101228 **
10763072-C-T **
27484492-TTGTG-T 25338345-TTGTG-T P1_Y2 14×TG**
10747986-C-G **
14926333-G-C 12814398-G-C **
14926334-G-A 12814399-G-A **
10839009-C-A **
10821971-C-G **
11038049-C-A **
28742532-G-A 26596385-G-A **
10769667-C-A **
10969964-C-T **
27847758-A-ATT 25701611-A-ATT P1_Y2 9×TG**
10748041-C-A **
10748058-T-A **
20645125-T-TC 18483239-T-TC P4_Prx **
15364690-C-A 13252810-C-A **
10955422-T-A **
22040856-C-A 19878970-C-A **
10791212-TTTCCA-T **
10748249-C-T **
16598716-A-T 14486836-A-T **
10801542-C-A **
28659874-C-A 26513727-C-A **
10942629-TTTCAC-T **
2688789-AT-A 2820748-AT-A 8×T**
21488772-C-A 19326886-C-A **
10801491-C-T **
10801537-C-A **
10994693-C-G **
18791153-C-A 16679273-C-A **
3218764-C-A 3350723-C-A **
13480491-C-A 11324815-C-A **
15622612-AAG-A 13510732-AAG-A **
24435646-T-TA 22289499-T-TA 9×A**
56842375-G-C **
2845271-A-T 2977230-A-T **
23455111-G-A 21293225-G-A **
18368704-C-A 16256824-C-A P6_Prx **
18928570-CAAAA-C 16816690-CAAAA-C 28×A**
28793817-A-T 26647670-A-T **
15081138-C-A 12969228-C-A **
23455119-G-A 21293233-G-A **
14531329-C-A 12419530-C-A **
20791852-G-T 18629966-G-T P4_Prx **
10663104-C-A **
10875768-T-G **
10956561-CTCCATTCCATTCCATTCCATTCCATTCCATTCCATTCCATTCCAT-C **
17588948-C-A 15477068-C-A **
10801731-CCTTTT-C **
18465502-T-G 16353622-T-G P6_Dst **
10759789-C-T **
10806670-CCATTCCTTTG-C **
28798319-A-G 26652172-A-G **
10977163-C-A **
14035028-C-A 11914322-C-A FT216229 **
11006495-A-G **
9752585-TTGTTG-T 9914976-TTGTTG-T **
10880357-C-A **
17355761-C-A 15243881-C-A **
10960362-T-C **
10748043-T-A **
36768-T-G **
10748025-C-CG **
10748026-C-CTTTG **
10748060-C-G **
22447692-G-T 20285806-G-T DYZ19 **
10883565-T-A **
10840666-C-A **
28793814-A-G 26647667-A-G **
10849125-C-A **
14926320-G-A 12814385-G-A **
21964006-A-G 19802120-A-G **
20217984-C-A 18056098-C-A P5_Dst **
18242080-C-A 16130200-C-A **
26421528-C-A 24275381-C-A P1_Y1 **
7081396-G-A 7213355-G-A **
10808948-C-T **
11668419-CAATGG-C **
10998101-C-T **
56851041-C-A **
4374229-C-A 4506188-C-A **
22994861-C-A 20832975-C-A **
26421518-G-T 24275371-G-T P1_Y1 **
28798264-A-G 26652117-A-G **
9015504-T-G 9177895-T-G **
14198261-C-A 12077555-C-A **
10878239-GATTCCATTCCATTCCATTCCATTCCATTCC-G **
14041499-A-C 11920793-A-C **
11020327-C-A **
14926332-G-A 12814397-G-A **
10973442-A-G **
10816271-C-A **
21362845-G-A 19200959-G-A **
5216349-C-A 5348308-C-A **
20673815-T-TA 18511929-T-TA P4_Prx **
18165862-C-A 16053982-C-A **
3158855-G-A 3290814-G-A **
3300404-G-T 3432363-G-T **
3305914-G-T 3437873-G-T **
3354195-G-T 3486154-G-T **
3497022-G-T 3628981-G-T **
3726621-C-A 3858580-C-A FTB61927 **
3879925-G-T 4011884-G-T **
3879975-G-T 4011934-G-T **
4049704-T-G 4181663-T-G **
4325708-G-A 4457667-G-A FT113547 **
4744313-C-A 4876272-C-A **
4841330-A-G 4973289-A-G **
4925156-G-T 5057115-G-T **
5065458-G-A 5197417-G-A **
5442103-G-T 5574062-G-T FT152710 **
5589184-G-T 5721143-G-T **
5701779-A-G 5833738-A-G **
5717762-A-C 5849721-A-C **
5773570-C-A 5905529-C-A **
5830379-A-G 5962338-A-G **
7132210-T-G 7264169-T-G **
7160894-C-CTTTT 7292853-C-CTTTT 16×T**
7166727-G-A 7298686-G-A **
7428150-A-C 7560109-A-C **
7451322-T-A 7583281-T-A IR1_L **
7451323-TGAG-T 7583282-TGAG-T IR1_L **
7573353-C-A 7705312-C-A **
9975830-T-A 10138221-T-A **
10653314-T-G **
10668210-C-A **
10669254-A-T **
10759808-TCC-T **
10759848-T-C **
10809349-ATTCC-A **
10809354-AT-A **
10836616-T-G **
10887345-T-TTCCAA **
10913114-C-A **
10921078-C-T **
10947362-C-T **
10960356-C-CCAAAA **
10994649-C-G **
10994688-C-A **
11006151-C-T **
11006494-C-T **
11006501-C-T **
11006505-A-C **
11033684-T-G **
11033703-TGCCAC-T **
13474483-T-C 11318807-T-C **
11652638-C-T FT213866 **
11672415-A-C **
11672645-C-T **
13906272-G-T 11785566-G-T **
13966587-C-A 11845881-C-A **
13974691-T-G 11853985-T-G **
14041150-C-A 11920444-C-A **
14109505-T-G 11988799-T-G **
14539260-T-G 12427461-T-G **
14550165-T-C 12438366-T-C **
14926298-C-G 12814363-C-G **
14926314-T-C 12814379-T-C **
14959680-C-T 12847755-C-T **
15178846-C-A 13066932-C-A **
15364685-C-A 13252805-C-A **
15937147-T-C 13825267-T-C **
16590693-C-G 14478813-C-G **
16612656-G-T 14500776-G-T **
16623471-G-T 14511591-G-T **
17735484-A-G 15623604-A-G **
17798762-C-A 15686882-C-A **
17798771-A-G 15686891-A-G **
18183384-C-A 16071504-C-A **
18188469-G-T 16076589-G-T **
18736531-T-C 16624651-T-C **
18976500-C-A 16864620-C-A **
19302112-A-G 17190232-A-G **
19412738-C-A 17300858-C-A FT79808 **
19416542-T-G 17304662-T-G **
19758825-C-A 17646945-C-A P5_Prx **
20084499-C-CTTT 17972619-C-CTTT P5_Dst 31×T**
21124022-C-A 18962136-C-A **
21963973-T-C 19802087-T-C **
21963978-A-G 19802092-A-G **
21964005-C-T 19802119-C-T **
22164376-C-CAAA 20002490-C-CAAA 22×A**
22203880-C-A 20041994-C-A **
22460530-C-A 20298644-C-A DYZ19 **
22460531-C-T 20298645-C-T DYZ19 **
22489789-C-G 20327903-C-G DYZ19 **
22660959-C-A 20499073-C-A **
23066413-A-G 20904527-A-G **
23455143-G-T 21293257-G-T **
23655440-CA-C 21493554-CA-C **
21752519-T-C **
25970735-T-G 23824588-T-G P1_Y1 **
26308517-C-A 24162370-C-A P1_Y1 **
26355315-T-C 24209168-T-C P1_Y1 **
26421540-T-A 24275393-T-A P1_Y1 **
26421551-G-T 24275404-G-T P1_Y1 **
27462013-T-A 25315866-T-A P1_Y2 **
27606988-A-G 25460841-A-G P1_Y2 **
27780467-A-G 25634320-A-G P1_Y2 **
27947627-TAAAAAAAC-T 25801480-TAAAAAAAC-T P1_Y2 **
28462107-C-G 26315960-C-G **
28508633-T-C 26362486-T-C **
28601768-T-G 26455621-T-G **
28668300-A-T 26522153-A-T **
28668322-TA-T 26522175-TA-T **
28755953-T-A 26609806-T-A **
28793810-A-C 26647663-A-C **
28798314-A-T 26652167-A-T **
28798321-G-A 26652174-G-A **
28798324-G-C 26652177-G-C **
56862409-C-T **
13483283-G-T 11327607-G-T ***
10684239-C-T ***
13483260-A-G 11327584-A-G ***
13483266-T-G 11327590-T-G ***
13483275-A-T 11327599-A-T ***
10973652-C-A ***
17950804-G-T 15838924-G-T ***
10959288-C-T ***
18687704-CA-C,CAA 16575824-CA-C,CAA 14×A***
10955447-A-T ***
2810435-ATT-A 2942394-ATT-A 15×T***
18094224-G-T 15982344-G-T ***
17843091-AT-A,ATT 15731211-AT-A,ATT 18×T***
10801746-C-G ***
9329002-C-A 9491393-C-A ***
10764551-ACTCC-A ***
13898754-GTTTTT-G 11778048-GTTTTT-G 26×T***
10959283-C-T ***
28805824-A-G 26659677-A-G ***
10799544-C-G,T ***
14463291-C-CTT 12342564-C-CTT 16×T***
18738114-CTT-C,CTTT 16626234-CTT-C,CTTT 19×T***
10955424-T-C ***
10801679-T-A ***
7197570-ATTT-A,AT 7329529-ATTT-A,AT 19×T***
10866328-A-G ***
10945993-C-T ***
10985140-A-G ***

In the table above, the meaning of the confidence field depends on whether the data comes from an FTDNA kit or an FGC kit. For FTDNA kits, + implies a "PASS" result with just one possible variant, * indicates a "PASS" but with multiple variants, ** indicates "REJECTED" with just a single variant, and *** indicates "REJECTED" with multiple possible variants. 'A*' are heterozygous variants not called by FTDNA, but still pulled from the VCF file. For FGC kits, + indicates over 99% likely genuine (95% for INDELs); * over 95% likely genuine (90% for INDELs); ** about 40% likely genuine; *** about 10% likely genuine. Manual entries read directly from a BAM file will be either + indicating positive, or * indicating that the data show a mixture of possible variants.

For the FTDNA kits, the BED data is encoded in the background color of the cells. Those cells with a white background have coverage, those with a grey background indicate no coverage in the BED file, and those with a pink background indicate the mutation is on the edge of a coverage region. These pink regions often indicate that the individual may be positive for a SNP even if there is no corresponding entry in the vcf file.

The combBED column indicates whether or not the mutation is a SNP and falls in the combBED region defined in Defining a New Rate Constant for Y-Chromosome SNPs based on Full Sequencing Data by Dmitry Adamov, Vladimir Guryanov, Sergey Karzhavin, Vladimir Tagankin, Vadim Urasin.

The McDonald BED column indicates whether or not the mutation is a SNP and falls in the BED region used by Dr. Iain McDonald in the age analysis he does for R-U106 men.