Block Information

There are many SNPs in this block that show up in the FGC tested men, but not the BigY tested men. That list of SNPs is: FGC11370, FGC11371, FGC11372, FGC11374, FGC11375, FGC11376, FGC11377, FGC11381, FGC11382, FGC11383, FGC11384, FGC11385, FGC11386, FGC11390, FGC11391, FGC11392, FGC11396, FGC11397, FGC11399, FGC11400, FGC11401, FGC11404, FGC11407, FGC12952, FGC11416 and FGC11418. All of these SNPs except for FGC11416 and FGC11418 show up in the 1000 genomes person, HG00107. Future testing is necessary to determine which of these SNPs belong in this block.

Upstream Blocks:

Children:

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Mutations in Block:

Names	Region	Unc	McDonald BED	combBED	POS-ANC-DER (hg19)	POS-ANC-DER (hg38)
FGC11388 Y8837			Y	Y	2851690-A-G	2983649-A-G
FGC11368 Y8838			Y	Y	7674522-G-A	7806481-G-A
Y8398 BY741			Y	Y	7907577-C-G	8039536-C-G
FGC11373 Y8839			Y	Y	8515748-A-G	8647707-A-G
Z2735					9754791-T-G	9917182-T-G
FGC11395 Y8842			Y	Y	14861066-C-A	12749132-C-A
FGC11394 Y8400			Y	Y	16803628-G-A	14691748-G-A
					17323920-G-GA	15212040-G-GA
FGC11398 Y8403			Y	Y	18866228-A-G	16754348-A-G
FGC11393 Y8405			Y	Y	19069867-A-G	16957987-A-G
FGC11411 Y8406			Y	Y	19116326-T-C	17004446-T-C
FGC11369 Y8407			Y	Y	19250454-A-G	17138574-A-G
					21477272-TTCATCATTG-T	19315386-TTCATCATTG-T
FGC11378 Y8408			Y	Y	21815867-A-G	19653981-A-G
FGC11379 Y8409			Y	Y	21826155-G-T	19664269-G-T
FGC11413			Y	Y	21853938-T-C	19692052-T-C
FGC11389 Y8840					13825112-G-A	11704406-G-A
BY31278 FGC68443					3148382-T-A	3280341-T-A
FGC11367 Y8399			Y	Y	14545037-A-G	12433238-A-G
FGC11387 Y8401			Y		17375416-A-G	15263536-A-G
FGC68444 BY28846	DYZ19				22228859-T-A	20066973-T-A
FGC68442	DYZ19				22223197-G-T	20061311-G-T
FGC11374 Y8397		Unc^†			4062768-G-C	4194727-G-C
FGC11376					4329664-C-G	4461623-C-G
FGC11375					4453520-C-T	4585479-C-T
FGC11400					4635950-C-T	4767909-C-T
FGC11390					5159399-C-T	5291358-C-T
FGC11401					5292940-A-T	5424899-A-T
FGC11381			Y	Y	6720487-C-T	6852446-C-T
FGC11391			Y	Y	6744583-G-T	6876542-G-T
FGC11392			Y	Y	7269305-T-C	7401264-T-C
FGC11397			Y	Y	7332619-G-A	7464578-G-A
FGC11399			Y		8176572-G-A	8308531-G-A
FGC11370			Y	Y	8774622-G-A	8906581-G-A
FGC11372					13580439-C-T	11424763-C-T
FGC11386			Y		14089989-C-T	11969283-C-T
FGC11385			Y		14422221-G-T	12301496-G-T
FGC11404			Y		14567377-C-A	12455577-C-A
FGC11377 Y8402			Y	Y	17492767-T-G	15380887-T-G
FGC12952				Y	18244628-T-C	16132748-T-C
FGC11384	P6_Gap				18406972-C-T	16295092-C-T
FGC11382 Y8404			Y	Y	18911494-A-T	16799614-A-T
FGC11371			Y	Y	21658486-T-C	19496600-T-C
FGC11396			Y		21955753-G-T	19793867-G-T
FGC11383					28730867-G-C	26584720-G-C
FGC11416			Y	Y	23054406-G-A	20892520-G-A
FGC11418			Y		23225692-C-T	21063806-C-T
	P2_r1				25211793-C-A	23065646-C-A
	P2_r2				25501205-G-T	23355058-G-T

*Mutations whose exact position can't be determined precisely from NGS tests, such as those in palindromes, are shown with a pink background.

^†For some mutations, their exact position on the tree is uncertain. The mutation may belong further upstream or all downstream branches may not be positive for it. This is often the case for SNPs/INDELs found in FGC kits or 1kG kits in regions not covered by BigY tests.

The combBED column indicates whether or not the mutation is a SNP and falls in the combBED region defined in Defining a New Rate Constant for Y-Chromosome SNPs based on Full Sequencing Data by Dmitry Adamov, Vladimir Guryanov, Sergey Karzhavin, Vladimir Tagankin, Vadim Urasin, The Russian Journal of Genetic Genealogy (Русская версия), Vol 6, No 2 (2014)/Vol 7, No 1 (2015).

The McDonald BED column indicates whether or not the mutation is a SNP and falls in the BED region used by Dr. Iain McDonald in the age analysis he does for R-U106 men.

Haplotype Data

The data below reveals the progression of changes in the haplotype. These are the inferred ancestral haplotypes for various upstream blocks. These inferred haplotypes are a work in progress, and any suggested modifications are appreciated. Mutations made from each upstream block are shown in sequence. The cell color is determined by the block in which the mutation took place.

	DYS393	DYS390	DYS19	DYS391	DYS385	DYS426	DYS388	DYS439	DYS389i	DYS392	DYS389ii	DYS458	DYS459	DYS455	DYS454	DYS447	DYS437	DYS448	DYS449	DYS464	DYS460	Y-GATA-H4	YCAII	DYS456	DYS607	DYS576	DYS570	CDY	DYS442	DYS438	DYS531	DYS578	DYF395S1	DYS590	DYS537	DYS641	DYS472	DYF406S1	DYS511	DYS425	DYS413	DYS557	DYS594	DYS436	DYS490	DYS534	DYS450	DYS444	DYS481	DYS520	DYS446	DYS617	DYS568	DYS487	DYS572	DYS640	DYS492	DYS565	DYS710	DYS485	DYS632	DYS495	DYS540	DYS714	DYS716	DYS717	DYS505	DYS556	DYS549	DYS589	DYS522	DYS494	DYS533	DYS636	DYS575	DYS638	DYS462	DYS452	DYS445	Y-GATA-A10	DYS463	DYS441	Y-GGAAT-1B07	DYS525	DYS712	DYS593	DYS650	DYS532	DYS715	DYS504	DYS513	DYS561	DYS552	DYS726	DYS635	DYS587	DYS643	DYS497	DYS510	DYS434	DYS461	DYS435
P312/S116	13	24	14	11	11-14	12	12	12	13	13	29	17	9-10	11	11	25	15	19	29	15-15-17-17	11	11	19-23	16	15	18	17	36-38	12	12	11	9	15-16	8	10	10	8	10	10	12	23-23	16	10	12	12	15	8	12	22	20	13	12	11	13	11	11	12	12	33	15	9	16	12	26	26	19	12	11	13	12	10	9	12	12	10	11	11	30	12	13	24	13	10	10	20	15	19	13	24	17	12	15	24	12	23	18	10	14	17	9	12	11

Age Analysis - Iain McDonald Method (Work in Progress)

Using the aging method developed by Iain McDonald, the median age of this block is 2793.5 YBP (844 BC). The 95% confidence interval is 1362 BC to 407 BC.

Measure	Age (YBP)
Mean	2797.9
Median	2793.5
Mode	2800.0